It may be harder to control your blood sugar during times of stress, such as fever, infection, injury, or surgery. Talk with your doctor about how to control your blood sugar if any of these occur. Do not change the dose of your medicine without checking with your doctor. Other Abnormal Laboratory Findings: Small reductions in hematocrit occurred more often in Acarbose Tablets-treated patients than in placebo-treated patients but were not associated with reductions in hemoglobin. Low serum calcium and low plasma vitamin B 6 levels were associated with Acarbose Tablets therapy but are thought to be either spurious or of no clinical significance.
Carefully follow the regular testing of urine or blood glucose schedules given to you by your health care provider. Unlike sulfonylureas or insulin, an overdose of Acarbose Tablets will not result in hypoglycemia. An overdose may result in transient increases in flatulence, diarrhea, and abdominal discomfort which shortly subside. In cases of overdosage the patient should not be given drinks or meals containing carbohydrates polysaccharides, oligosaccharides and disaccharides for the next 4-6 hours. A1c, complete blood counts should be performed periodically to check for side effects and monitor your response to therapy. Check your blood or urine sugar levels regularly as directed by your doctor or pharmacist.
If swallowing is difficult, then the capsule may be opened and the contents mixed in a small amount of liquid or soft food that does not need to be chewed such as room-temperature applesauce. Do not mix the contents of the capsule with alkaline food or liquid such as milk, ice cream, tea. Reclining after eating may help prevent light-headedness. Tell your doctor about all kind of medications you are taking, as these may interfere with the ability of Glycomet Generic Glucomin to control your blood sugar level. In initiating treatment for type 2 diabetes mellitus, diet should be emphasized as the primary form of treatment. Caloric restriction and weight loss are essential in the obese diabetic patient. Proper dietary management alone may be effective in controlling blood glucose and symptoms of hyperglycemia. The importance of regular physical activity when appropriate should also be stressed.
Remember that your doctor has prescribed this because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. Patients Receiving Sulfonylureas or Insulin: Sulfonylurea agents or insulin may cause hypoglycemia. Acarbose Tablets given in combination with a sulfonylurea or insulin will cause a further lowering of blood glucose and may increase the potential for hypoglycemia. If hypoglycemia occurs, appropriate adjustments in the dosage of these agents should be made. Symptoms of low blood sugar include anxiety; behavior change similar to being drunk; blurred vision; cold sweats; confusion; cool, pale skin; difficulty in thinking; drowsiness; excessive hunger; fast heartbeat; headache continuing; nausea; nervousness; nightmares; restless sleep; shakiness; slurred speech; or unusual tiredness or weakness.
Digestive Tract: Gastrointestinal symptoms are the most common reactions to Acarbose Tablets. Discuss the risks and benefits with your doctor. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Take this medication by mouth, usually 3 times a day at the start with the first bites of each main meal or as directed by your doctor. Acarbose corresponding to 10 times the dose in man, based on body surface area showed no evidence of embryotoxicity and there was no evidence of teratogenicity at a dose 32 times the dose in man based on body surface area. There are, however, no adequate and well-controlled studies of Acarbose Tablets in pregnant women. Because animal reproduction studies are not always predictive of the human response, this drug should be used during pregnancy only if clearly needed. Because current information strongly suggests that abnormal blood glucose levels during pregnancy are associated with a higher incidence of congenital anomalies as well as increased neonatal morbidity and mortality, most experts recommend that insulin be used during pregnancy to maintain blood glucose levels as close to normal as possible. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Acarbose is also contraindicated in patients with inflammatory bowel disease, colonic ulceration, partial intestinal obstruction, or in patients predisposed to intestinal obstruction. The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. If your symptoms do not improve or if they become worse, check with your doctor. Severe hypoglycemia may require the use of either intravenous glucose infusion or glucagon injection. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs including any herbal medicines or supplements or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The information contained in the Truven Health Micromedex products as delivered by Drugs.
Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. What other drugs will affect acarbose? WebMD User Reviews should not be considered as medical advice and are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences may be a helpful health information resource but they are never a substitute for professional medical advice from a qualified healthcare provider. Initial Dosage: The recommended starting dosage of Acarbose Tablets is 25 mg given orally three times daily at the start with the first bite of each main meal. However, some patients may benefit from more gradual dose titration to minimize gastrointestinal side effects. What should I discuss with my healthcare provider before taking acarbose Precose? Your doctor may want you to stop taking acarbose for a short time if you become ill, have a fever or infection, or if you have surgery or a medical emergency. moduretic
Tell your doctor or dentist that you take acarbose before you receive any medical or dental care, emergency care, or surgery. This list is not complete and other drugs may affect your blood sugar or interact with acarbose. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Acarbose Tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Your pharmacist can provide more information about acarbose. Drinking alcohol may cause severe low blood sugar. Discuss this with your health care team. Diarrhea, gas, upset stomach, constipation, or stomach pain may occur in the first few weeks of treatment as your body adjusts to this medication but usually improve with time. Follow your prescribed diet to help lessen these side effects. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. At first the dose is 25 milligrams mg three times a day, at the start of each main meal. Your dose may then be adjusted by your doctor. Acarbose Tablets should be adjusted at 4-8 week intervals based on one-hour postprandial glucose or glycosylated hemoglobin levels, and on tolerance. HbA1c levels from baseline throughout a one-year study in patients with type 2 diabetes mellitus when used in combination with: A diet alone; B sulfonylurea; C metformin; or D insulin. fludrocortisone online money order fludrocortisone
Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition. If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting acarbose. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease. Studies in healthy volunteers have shown that Acarbose Tablets have no effect on either the pharmacokinetics or pharmacodynamics of nifedipine, propranolol, or ranitidine. Acarbose Tablets did not interfere with the absorption or disposition of the sulfonylurea glyburide in diabetic patients. Acarbose Tablets may affect digoxin bioavailability and may require dose adjustment of digoxin by 16% 90% confidence interval: 8-23% decrease mean C max of digoxin by 26% 90% confidence interval: 16-34% and decreases mean trough concentrations of digoxin by 9% 90% confidence limit: 19% decrease to 2% increase. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Symptoms of high blood sugar hyperglycemia include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell your doctor right away. Your dosage may need to be increased or you may need other drugs. FDA pregnancy category B. Acarbose is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. 'Multum' is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Its action is quite different from sulfonylureas and metformin. By slowing the digestion of carbohydrates in the small intestine, the blood sugar rise after a meal is lessened. Acarbose works by inhibiting enzymes in the intestine that break carbohydrates down, so glucose levels rise more slowly and the person's own internal production of insulin can more easily respond. Sorry I couldn't provide a more sound scientific basis, but there are foods around that are not expensive, not genetically engineered, and provided very stable carbohydrate management without having to use a myriad of advanced concoctions. There may be a time when you need emergency help for a problem caused by your diabetes. You need to be prepared for these emergencies. It is a good idea to wear a medical identification ID bracelet or neck chain at all times. Also, carry an ID card in your wallet or purse that says that you have diabetes and a list of all of your medicines. Overdose symptoms may include bloating, gas, or stomach discomfort. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. If you have severe hypoglycemia and cannot eat or drink, use a glucagon injection. Where can I get more information?
Also, the fewer variables in your program, the easier your successes and failures are to track. Especially since I cannot stand seafood. The dosage is based on your medical condition, weight, and response to therapy. Your dose may be gradually increased to determine the most effective dose for you. The manufacturer recommends that you do not take more than 300 milligrams per day. Check your blood sugar carefully during times of stress, travel, illness, surgery or medical emergency, vigorous exercise, or if you drink alcohol or skip meals. These things can affect your glucose levels and your dose needs may also change. Do not change your medication dose or schedule without your doctor's advice. Carry hard candy or glucose tablets with you in case you have low blood sugar. Other sugar sources include orange juice and milk. Be sure your family and close friends know how to help you in an emergency. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Your medication needs may change if you become sick or injured, if you have a serious infection, or if you have any type of surgery. Do not change your dose or stop taking acarbose without first talking to your doctor. Acarbose Tablets themselves do not cause hypoglycemia even when administered to patients in the fasted state. Sulfonylurea drugs and insulin, however, can lower blood sugar levels enough to cause symptoms or sometimes life-threatening hypoglycemia. Because Acarbose Tablets given in combination with a sulfonylurea or insulin will cause a further lowering of blood sugar, it may increase the hypoglycemic potential of these agents. Hypoglycemia does not occur in patients receiving metformin alone under usual circumstances of use, and no increased incidence of hypoglycemia was observed in patients when Acarbose Tablets were added to metformin therapy. The risk of hypoglycemia, its symptoms and treatment, and conditions that predispose to its development should be well understood by patients and responsible family members. If side effects occur with Acarbose Tablets, they usually develop during the first few weeks of therapy. They are most commonly mild-to-moderate gastrointestinal effects, such as flatulence, diarrhea, or abdominal discomfort, and generally diminish in frequency and intensity with time. Glycomet may cause side effects. Acarbose is used to treat type 2 diabetes. Acarbose is sometimes used in combination with insulin or other diabetes medications you take by mouth. The fraction of Acarbose that is absorbed as intact drug is almost completely excreted by the kidneys. When Acarbose was given intravenously, 89% of the dose was recovered in the urine as active drug within 48 hours. In contrast, less than 2% of an oral dose was recovered in the urine as active that is, parent compound and active metabolite drug. This is consistent with the low bioavailability of the parent drug. The plasma elimination half-life of Acarbose activity is approximately 2 hours in healthy volunteers. purchase repaglinide for dogs repaglinide
Acarbose slows the digestion of carbohydrates in the body, which helps control blood sugar levels. If you finish a meal and you have forgotten to take the medicine, do not take the missed dose. Instead, take the next dose at the beginning of your next meal, as scheduled. Acarbose may also be used for purposes not listed in this medication guide. How should I take acarbose? If symptoms of low blood sugar occur, eat glucose tablets or gel or honey, or drink fruit juice to relieve the symptoms. Table sugar sucrose or regular nondiet soft drinks will not work. Also, check your blood for low blood sugar. Glucagon is used in emergency situations when severe symptoms such as seizures convulsions or unconsciousness occur. Symptoms of high blood sugar include blurred vision; drowsiness; dry mouth; flushed, dry skin; fruit-like breath odor; increased urination; ketones in urine; loss of appetite; stomachache, nausea, or vomiting; tiredness; troubled breathing rapid and deep; unconsciousness; or unusual thirst. If you miss a dose of acarbose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. order now online clarinex mastercard
The cause of this rapid swing in may be worse when eating sweets or other simple carbohydrates. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Call your doctor for medical advice about side effects. You may report side effects to Strides Pharma Inc. at 1-877-244-9825 or go to www. Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Low blood sugar hypoglycemia can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, confusion, irritability, dizziness, or feeling shaky. Always keep a source of dextrose D-glucose with you in case you have low blood sugar. When taking acarbose, dextrose will work better than cane sugar or table sugar in treating hypoglycemia. Sources of dextrose include honey, dates, raisins, plums, dried prunes, grapes, or glucose tablets. Be sure your family and close friends know how to help you in an emergency. Use acarbose as directed by your doctor. Check the label on the medicine for exact dosing instructions. The presence of other medical problems may affect the use of acarbose. Symptoms of an early phase happen because food is rapidly "dumping" into the small intestine. Laboratory Tests: Therapeutic response to Acarbose Tablets should be monitored by periodic blood glucose tests. What are the possible side effects of acarbose Precose? If you take acarbose with insulin or other diabetes medications, your blood sugar could get too low. Check with your pharmacist about how to dispose of unused medicine. In case of overdose, do not eat or drink anything containing carbohydrates for the next 4 to 6 hours.
If you have not already been diagnosed with the dumping syndrome, and you have confusion, dizziness, rapid heartbeat, or fainting, get immediate medical help. Call 911 right away. Avoid taking a digestive enzyme such as pancreatin, amylase, or lipase at the same time you take acarbose. These enzymes can make it harder for your body to absorb acarbose. Products that contain digestive enzymes include Arco-Lase, Cotazym, Donnazyme, Pancrease, Creon, and Ku-Zyme. Diabetes patients - Carry an ID card at all times that says you have diabetes. Check your blood sugar levels as directed by your doctor. If they are often higher than they should be and you take acarbose exactly as prescribed, tell your doctor. It is a group of symptoms that may result from having part of your removed or from other surgery involving the stomach. The symptoms range from mild to severe and often subside with time. Although you may find dumping syndrome alarming at first, it is not life threatening. You can control it by making changes in what and how you eat. Consult your doctor because this may require a change in your treatment plan, medications, or blood sugar testing. PrecoseR acarbose tablets to existing therapies for patients with type II diabetes improves long-term blood glucose control, according to final results of the United Kingdom Prospective Diabetes Study. Acarbose is metabolized exclusively within the gastrointestinal tract, principally by intestinal bacteria, but also by digestive enzymes. A fraction of these metabolites approximately 34% of the dose was absorbed and subsequently excreted in the urine. At least 13 metabolites have been separated chromatographically from urine specimens. The major metabolites have been identified as 4-methylpyrogallol derivatives that is, sulfate, methyl, and glucuronide conjugates. One metabolite formed by cleavage of a glucose molecule from Acarbose also has alpha-glucosidase inhibitory activity. This metabolite, together with the parent compound, recovered from the urine, accounts for less than 2% of the total administered dose. It is not known whether acarbose passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using acarbose. This may not be a complete list of all interactions that may occur. Ask your health care provider if acarbose may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. The information on this page is not a substitute for the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that a drug or drug combination is safe, effective or appropriate for any given patient. Drugs. The beans are all very fibrous, complex carbs and release the sugars very slowly - stick to the ribs as they say. Because its mechanism of action is different, the effect of Acarbose Tablets to enhance glycemic control is additive to that of sulfonylureas, insulin or metformin when used in combination. In addition, Acarbose Tablets diminish the insulinotropic and weight-increasing effects of sulfonylureas. cost skelaxin virginia
Lack of interaction between thioctic acid, glibenclamide and acarbose. Follow carefully the special meal plan your doctor gave you. This is the most important part of controlling your condition, and is necessary if the medicine is to work properly. Also, exercise regularly and test for sugar in your blood or urine as directed. Acarbose Tablets are available as 25 mg, 50 mg or 100 mg, circular biconvex tablets. Each tablet strength is white to off white in color. The 25 mg tablet is engraved with 'P210' on one side and '25' on the other side. The 50 mg tablet is engraved with 'P211' on one side and '50' on the other side. The 100 mg tablet is engraved with 'P212' on one side and '100' on the other side. Acarbose Tablets are available in bottles of 100. Adding the a-glucosidase inhibitor, Bayer Corp. Once an effective and tolerated dosage is established, it should be maintained. pdox.info maxalt
Precose decreases peaks in blood glucose levels that occur after eating by delaying absorption of carbohydrates sugar and starches into the bloodstream. Also avoid dairy products and alcohol. And avoid eating solids and drinking liquids during the same meal. In fact, don't drink 30 minutes before and 30 minutes after meals. Certain drugs tend to produce hyperglycemia and may lead to loss of blood glucose control. These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel-blocking drugs, and isoniazid. When such drugs are administered to a patient receiving Acarbose Tablets, the patient should be closely observed for loss of blood glucose control. When such drugs are withdrawn from patients receiving Acarbose Tablets in combination with sulfonylureas or insulin, patients should be observed closely for any evidence of hypoglycemia. Do not take more capsules in a day than prescribed by your doctor. Your condition will not improve any faster, and your risk of side effects will increase. Patients Receiving Sulfonylureas or Insulin: Sulfonylurea agents or insulin may cause hypoglycemia. Acarbose Tablets given in combination with a sulfonylurea or insulin may cause a further lowering of blood glucose and may increase the potential for hypoglycemia. If hypoglycemia occurs, appropriate adjustments in the dosage of these agents should be made.
Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office. Hyperglycemia high blood sugar may occur if you do not take enough or skip a dose of your antidiabetic medicine, overeat or do not follow your meal plan, have a fever or infection, or do not exercise as much as usual. Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. In contrast to sulfonylureas, Acarbose Tablets do not enhance insulin secretion. The antihyperglycemic action of Acarbose results from a competitive, reversible inhibition of pancreatic alpha-amylase and membrane-bound intestinal alpha-glucoside hydrolase enzymes. Pancreatic alpha-amylase hydrolyzes complex starches to oligosaccharides in the lumen of the small intestine, while the membrane-bound intestinal alpha-glucosidases hydrolyze oligosaccharides, trisaccharides, and disaccharides to glucose and other monosaccharides in the brush border of the small intestine. In diabetic patients, this enzyme inhibition results in a delayed glucose absorption and a lowering of postprandial hyperglycemia. Using acarbose with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Precose slows the digestion of carbohydrate sugars and starches in the small intestine. Do not share this medication with others. Ask your doctor how to adjust your acarbose dose if needed. Do not change your medication dose or schedule without your doctor's advice. Information for Patients: Patients should be told to take Acarbose Tablets orally three times a day at the start with the first bite of each main meal. Eat five or six small meals or snacks a day. For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products. Macrovascular Outcomes: There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with Acarbose Tablets or any other anti-diabetic drug. What is the most important information I should know about acarbose Precose? cheap plavix toronto
As a species, we have been eating "modern" food for only about the past 75 years. TA and S--TA as well as glibenclamide concentrations were measured with specific analytical methods. RESULTS: There was no clinically relevant change of TA enantiomer pharmacokinetics by glibenclamide or acarbose. Also, glibenclamide pharmacokinetics were not altered by TA to a clinically meaningful extent. Plasma insulin and glucose concentrations did not indicate an interaction between TA and glibenclamide or TA and acarbose. Glibenclamide had the expected effect on insulin and glucose levels independent of comedication. There were only minor and short lasting adverse events with the majority being expected hypoglycaemic symptoms occurring during the treatments with glibenclamide. Mostly you will be prescribed one 500mg Glycomet Generic Glucomin tablet 3 times a day, while the 850mg tablets are usually taken twice daily to give effective diabetes control. You should use Glycomet Generic Glucomin only as directed by your doctor. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. If you also take charcoal or digestive enzyme preparations eg, amylase, pancreatin ask your doctor or pharmacist how to take them with acarbose. United States and its territories. Indications, uses and warnings on Drugs. ULN, and greater than 3 times the ULN occurred in 14%, 6%, and 3%, respectively, of Acarbose Tablets-treated patients as compared to 7%, 2%, and 1%, respectively, of placebo-treated patients. Although these differences between treatments were statistically significant, these elevations were asymptomatic, reversible, more common in females, and, in general, were not associated with other evidence of liver dysfunction. In addition, these serum transaminase elevations appeared to be dose related. Renal Impairment: Plasma concentrations of Acarbose Tablets in renally impaired volunteers were proportionally increased relative to the degree of renal dysfunction. Drink plenty of fluids while taking this medication unless your doctor tells you otherwise. Do NOT take more than the recommended dose without checking with your doctor. omnicef
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Acarbose Tablets were statistically significantly different from placebo at all doses with respect to effect on one-hour postprandial plasma glucose. Also watch for signs of high blood sugar hyperglycemia such as increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
The way in which these drugs work is also the major source of their side effects. Although these drugs are very safe, their side effects can be annoying. If digestion is greatly inhibited, this may cause abdominal bloating, gas and diarrhea. The alpha glucosidase inhibitors should always be started on a minimal dose, often half of the smallest tablet, and then gradually increased over time. This greatly minimizes gastric side effects; side effects also tend to decrease over time. Acarbose may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking acarbose. Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office. Visit your doctor regularly.
Doing so can irritate the and also change the way the medication works. What other drugs will affect acarbose Precose? Clinical Experience in Type 2 Diabetes Mellitus Patients on Monotherapy, or in Combination with Sulfonylureas, Metformin or Insulin: Acarbose Tablets were studied as monotherapy and as combination therapy to sulfonylurea, metformin, or insulin treatment. The treatment effects on HbA1c levels and one-hour postprandial glucose levels are summarized for four placebo-controlled, double-blind, randomized studies conducted in the United States in Tables 2 and 3, respectively. The placebo-subtracted treatment differences, which are summarized below, were statistically significant for both variables in all of these studies.
Therefore, treatment of these patients with Acarbose Tablets is not recommended. Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Acarbose does not cause low blood sugar hypoglycemia. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; bloody stools; severe or persistent diarrhea or constipation; severe stomach pain; unusual bleeding or bruising. Acarbose Tablets should be taken three times daily at the start with the first bite of each main meal. Acarbose Tablets should be started at a low dose, with gradual dose escalation as described below, both to reduce gastrointestinal side effects and to permit identification of the minimum dose required for adequate glycemic control of the patient. If the prescribed diet is not observed, the intestinal side effects may be intensified. If strongly distressing symptoms develop in spite of adherence to the diabetic diet prescribed, the doctor must be consulted and the dose temporarily or permanently reduced.